Addison’s Disease


What is Addison’s Disease?

Addison’s Disease is primarily a deficiency of hormones produced by the adrenal glands. There is increased excretion of salt.

Causes of Addison’s Disease

1. Anatomical destruction of glands: Unknown, surgery, tuberculosis, fungal infections,
hemorrhage, cancer.
2. Failure to produce hormones: congenital.
3. Poor functions of the pituitary gland.
4. Excess intake of steroids.

Clinical Features of Addison’s Disease

1. Weakness, hypotension, fatigue.
2. Pigmentation of the skin and mucous membranes.
3. Weight loss.
4. Loss of appetite, vomiting.
5. Pain abdomen.
6. Diarrhoea/constipation, salt craving.
7. Faintness.

Management of Addison’s Disease

Hormone replacement in hospital.

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