What is Cushing’s Disease?

Increased size of adrenal tissue due to pituitary gland abnormalities or secondary to non-endocrine tumours in other organs producing excess hormones.

Causes of Cushing’s Disease

  • Adrenal gland cancer.
  • Excess use of steroid drugs.
  • Clinical Features of Cushing’s Disease
  • Full face, redness, and puffiness.
  • Obesity with an excess deposit of fat behind the neck.
  • High BP.
  • Frank diabetes, peptic ulcer.
  • Fatigue and muscle weakness.
  • Weakened bones.
  • Emotional changes, depression, confusion.
  • Menstrual irregularities.
  • Acne, increased body and facial hair.

Management of Cushing’s Disease

Investigation and treatment in a hospital.

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