Klonopin (clonazepam) is in a class of drugs called benzodiazepines. Clonazepam is used to reserve seizures. It also is used to mitigate anxiety. It is a highly puissant anticonvulsant, amnestic, and anxiolytic. Clonazepam also is used to treat symptoms of Parkinson's disease, vellicating, schizophrenia, and pain management. Klonopin is indicated for the treatment of panic disorder, with or without agoraphobia, as outlined in DSM-IV. Panic disorder is distinguished by the occurrence of unanticipated panic attacks and associated concern about having additional attacks, worry about the implications or consequences of the attacks, and/or a significant change in behavior related to the attacks.
The efficacy of Klonopin was predicated in two 6- to 9-week trials in panic disorder patients whose diagnoses corresponded to the DSM-IIIR category of panic disorder. Unlike most other benzodiazepines clonazepam appears to also have effect on the neurotransmitter serotonin. Clonazepam is metabolised by the liver to dormant metabolites, that are secreated mainly in the urine. Less than 0.5% of a dose is excreted in the urine unaltered and from 9 to 27% of a dose may be excreted in the feces.
The half-life of the parent compound ranges from approximately 18 to 50 hours. Clonazepam is occassionally used as a treatment for insomnia, due to its sedative effects are relatively weak compared to other benzodiazepines. Clonazepam has been dictated in order to alleviate the side effects of certain antipsychotic agents used in the treatment of Schizophrenia.
Klonopin is also present as an orally disintegrating tablet containing 0.125 mg, 0.25 mg, 0.5 mg, 1 mg or 2 mg clonazepam. Each orally disintegrating tablet also have gelatin, mannitol, methylparaben sodium, propylparaben sodium and xanthan gum. The most commonly noted side effects of clonazepam is dizziness (one-third of patients), weakness, and instability. Other side effects include a feeling of depression, loss of orientation, headache, and sleep insaneness. Clonazepam, and all benzodiazepines, interact with other medications and drugs which slack the brain's processes, such as alcohol, barbiturates, and narcotics.
- The dose of Klonopin will be different for different patients.
- Adults and teenagers - A endorsed adult maintenance dose is 8 to 10 mg/day in 3 divided doses. Dosages in excess of 20 mg/day should be administered with admonish.
- Children - Iinitial dose for infants and children (up to 10 years of age or 30 kg) should be between 10 and 30 mcg/kg/day and should not exceed 50 mcg/kg/day given in 2 or 3 divided doses.
Side Effects of Klonopin
- Dry mouth
- Upset stomach
- Sleep disturbance.
Warnings and precautions before taking Klonopin
Clonazepam, and all benzodiazepines, interact with other medications and drugs which slow the brain's processes, such as alcohol and barbiturates. Cigarette smoking may decrease the efficaciousness of this drug. When taken by pregnant women in their first trimester. Clonazepam is best avoided in the first trimester, and possibly throughout pregnancy. Stopping the drugabruptly can worsen your condition and cause withdrawal symptoms (anxiousness, sleeplessness, and irritability).
Seek emergency clinical attention if an overdose is suspected. Signs of a Klonopin (clonazepam) overdose may include drowsiness, dizziness, confusion, a slow heart beat, troubling breathing, difficulty walking and talking, an appearance of being drunk, and unacquaintance. Klonopin (clonazepam) mayaggrandize the effects of other drugs that cause drowsiness or dizziness, including alcohol, sedatives (used to treat insomnia).